Endocrine Abstracts

Hyperthyroidism in pregnancy is associated with increased foetal and maternal morbidity. Hyperthyroidism occurs in 0.2–0.6% of pregnancies. This suggests that based on 23,000 deliveries in the 3 major Dublin maternity hospitals that 40–60 cases per year would be expected to be at risk of a poor outcome from hyperthyroidism.To clarify those factors associated with poor outcome in hyperthyroidism in pregnancy we undertook an audit of 53 cases of ...

Standard Autonomic Function tests AFT may not detect subclinical CAN. Modalities exist (Frequency Domain) using PSA of HRV, which may detect subclinical CAN.We performed standard AFTs (HR response to deep breathing, Valsalva, Tilt at 1 min and 6 min) and PSA of HRV on these tests in 46 subjects (29 DM and 17 Controls) matched for age and sex. We sought to establish if those DM subjects considered normal by AFT would exhibit abnormalities in PSA of HRV. W...

IgG4 related hypophysitis is a recently described entity belonging to the IgG4 related diseases. It is characterised by markedly elevated serum IGG4 levels and tissue infiltration by IgG4 positive plasma cells. To date, 34 cases of IgG4 related hypophysitis have been described but only a handful were in women or biopsy proven. We describe a case of a 58 year old woman who presented with transient headache. She also complained of polyuria and nocturia. She had a thyroidectomy f...